Anti-Glomerular Basement Membrane Disease

An autoimmune disease of the KIDNEY and the LUNG. It is characterized by the presence of circulating autoantibodies targeting the epitopes in the non-collagenous domains of COLLAGEN TYPE IV in the basement membranes of kidney glomeruli (KIDNEY GLOMERULUS) and lung alveoli (PULMONARY ALVEOLI), and the subsequent destruction of these basement membranes. Clinical features include pulmonary alveolar hemorrhage and glomerulonephritis.

Also Known As:

Goodpasture's Syndrome; Goodpasture Syndrome; Anti GBM Disease; Syndrome, Goodpasture's; Lung Purpura with Nephritis; Anti Glomerular Basement Membrane Disease; Goodpastures Syndrome; Syndrome, Goodpasture; Anti-GBM Disease

Respiratory Tract Diseases: 6015
- Lung Diseases: 22246
  - Interstitial Lung Diseases: 8435
    - Anti-Glomerular Basement Membrane Disease: 918
Urogenital Diseases: 126
- Urologic Diseases: 799
  - Kidney Diseases: 12250
    - Nephritis: 6086
      - Glomerulonephritis: 13339
        Anti-Glomerular Basement Membrane Disease: 918
- Female Urogenital Diseases and Pregnancy Complications
  - Female Urogenital Diseases
    - Urologic Diseases: 799
      - Kidney Diseases: 12250
        Nephritis: 6086
        Glomerulonephritis: 13339
        Anti-Glomerular Basement Membrane Disease: 918
- Male Urogenital Diseases
  - Urologic Diseases: 799
    - Kidney Diseases: 12250
      - Nephritis: 6086
        Glomerulonephritis: 13339
        Anti-Glomerular Basement Membrane Disease: 918
Immune System Diseases: 4321
- Autoimmune Diseases: 34618
  - Anti-Glomerular Basement Membrane Disease: 918

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Domingo Diaz Research Topics

Disease

Drug/Important Bio-Agent (IBA)